Human Blood vs. Snake Venom!

自分の血と毒蛇の毒を混ぜるとかいう体を張ったCoyoteの企画を見てみましょう。

通常血液が空気中の酸素にexposed曝されると 、凝固coagulateして血の塊clotができるわけですが、毒蛇の毒には凝固を止めてしまう効果anticoagulantがあり、血が止まらなくなってしまします。

 それでは今日もYouTube英語を楽しんでいきましょう！

というか、YouTubeって流血NGじゃなかったでしたっけ？ｗ

00:00
today I'm going to take eight vials of
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my own blood and add to that blood venom
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from three of the most potent pit vipers
00:09
here in the United States we have a
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medic that is going to stick me with a
00:13
needle and drop these eight vials of
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blood and right now I'm feeling very
00:16
very nervous and a little squeamish and
00:19
it might pass out during this process
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okay here we go giving my blood for
00:23
science
00:40
today we're at the reptile Discovery
00:42
Center located in d'Alene Florida this
00:46
serpentarium is home to several of the
00:48
world's most dangerous snakes and
00:50
earlier today I assisted in milking the
00:53
venom of three pit vipers that are
00:55
frequently encountered in the eastern
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United States the Copperhead is
01:01
fantastic water moccasin gonna get most
01:03
on ok and the Eastern diamondback
01:06
rattlesnake is sent to their Med toxin
01:14
venom laboratory where it is turned into
01:16
life-saving anti-venom but today we're
01:19
going to perform an experiment unlike
01:21
anything you have ever seen ok crew is
01:27
all set up
01:31
alright guys so today's experiment is
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going to show us what happens when snake
01:37
venom mixes together with human blood
01:39
I've always been curious what happens
01:41
when a snake bites you and that venom
01:43
enters into the bloodstream so today
01:45
what we're gonna do is take eight vials
01:47
of my blood we're gonna create a control
01:50
and then we're going to mix venom into
01:51
three different files and show you
01:53
exactly what happens I know it seems
01:55
like how you get to the point already
01:57
I'm only prolonging this because I'm so
01:59
squeamish around needles you guys have
02:01
no idea how nervous I am right now I
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could take bulleting it stings I can
02:05
take bites from giant desert centipede
02:06
when it comes to sticking a needle into
02:08
my arm nothing that makes my skin crawl
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more than that we've got a medic on set
02:13
with us and she is going to safely draw
02:16
out my blood okay okay
02:28
I'm already hot I'm sweating bullets
02:29
right now like more nervous than I was
02:31
four ants centipedes like worst day
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okay yes I can be ready
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[Music]
02:48
find a happy place find a happy place is
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that it is this consider a lot of blood
02:54
for one sitting okay I'm gonna put the
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GoPro down it what this is to see what's
03:03
happening
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I can't look with my own eyes I can't
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bear I can't feel my arm like it should
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I be doing anything with my arm for what
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is it out oh my god she's gonna like
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squirt blood if you oh my god look at
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all those tubes of blood
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holy mackerel but what we're gonna do
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now is head down the hallway meet up
03:33
with Carl and move to step two of this
03:36
experiment holy cow look at all of these
03:39
vials of blood that is so much coyote
03:42
that is spilled out in the name of
03:44
science okay Carl I am back with eight
03:49
vials of my blood now we're only going
03:52
to need four for this experiment so I'll
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put these other four over here as a
03:56
backup and we've got the entire
03:58
experiment set up we've got three vials
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that contain Copperhead water moccasin
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and Eastern Diamondback venom eventually
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that blood is going to trickle down this
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board that we've created but before we
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get there let's talk about these Venom's
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and why they're so potentially dangerous
04:12
okay so coyote all three of these snakes
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cause you to bleed cause you to
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hemorrhage and hemorrhaging is dangerous
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for a host of reasons your blood doesn't
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clot you're losing blood from your blood
04:23
vessels your blood corpuscles are being
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broken apart your red blood cells are
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being licensed they're not carrying
04:29
oxygen to your tissues they all cause
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you to hemorrhage they do it a little
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differently the mechanisms that work do
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it a little differently but they all
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caused that significant bleeding
04:39
coagulopathy problem okay is complex but
04:43
sounds very painful at the same time
04:45
obviously a lot of pain is experienced
04:48
with a bite from any one of these snake
04:49
species okay so I'm definitely going to
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put on my safety goggles for this part I
04:54
am going to open up this vial and expose
04:57
the venom now
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I have this one labeled Copperhead and
05:00
you'll see I also have a blunt tipped
05:02
needle the reason for that is if this
05:05
was sharp and I were to accidentally
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prick myself
05:07
that's just like a snake Fang well you
05:09
don't want to do is in venom eight
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yourself while working with venom
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so I'm gonna just oh man makes your hand
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nervous just pick up and hold what that
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is right there that is some very potent
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venom now Carla might need your
05:21
assistance if you can just tilt that a
05:23
tiny bit until I'm able to get I think
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that's enough yep that's probably more
05:31
than a full snake bite right there sir
05:33
okay so there is our Copperhead venom
05:36
whew one down our next one is going to
05:41
be the water moccasin Wow look at that
05:44
venom yield gives you a sense of how
05:47
dangerous cotton mouston be and part of
05:48
that equation again is you that's three
05:51
snakes of course but even still toxic
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little mix right Oh got a little drip
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coming put that there and now we are
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going to bring up the most potent of
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them all the Eastern Diamondback whoo
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this is the big one right here all right
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[Music]
06:17
there we go and that right there would
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be enough venom to kill you wouldn't it
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okay so we've got our three syringes of
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venom wind-up Thank You Carl
06:29
oh this is ah keeping hands steady it's
06:33
not an easy thing okay so the first one
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our green is going to be the Copperhead
06:41
okay there we go
06:44
dangerous little tube right there okay
06:46
moving on to the water moccasin labeled
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yellow caution
06:50
water moccasins can be deadly definitely
06:53
not a snake you ever want to trifle with
06:55
in the wild admire these guys from a
06:58
very safe distance okay there we go all
07:05
right
07:05
that is moccasin venom going into my
07:08
blood and last but certainly not least
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will be the Eastern diamondback
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rattlesnake
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it's still a very very dangerous syringe
07:19
right there there's still some venom
07:20
residue okay there we go that is Eastern
07:24
Diamondback venom going into my blood
07:28
okay well let's take 15 minutes we will
07:31
return and step three of this experiment
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will tell us exactly what happens from a
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visual perspective when you add snake
07:38
venom to human blood but I know a lot of
07:40
you out there is said before coyote
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you've been bitten and stung by so many
07:44
things get bitten by a venomous snake
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now Carl I want to open up this
07:48
conversation to you to say is everybody
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out there watching how crazy is that
07:54
notion of intentionally being bitten by
07:56
a venomous snake and just so we're clear
07:58
guys I'm never going to intentionally
07:59
take on a bite like something from
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Copperhead of water moccasin or
08:03
rattlesnake and tell us why this is so
08:05
damaging because insects stings and
08:08
snake bites are very different things
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and so inside Venom's to a large degree
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evolved to cause pain and they and
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basically what they're trying to do is
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get you
08:17
from perhaps their nest or something of
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that nature snake venoms evolved to
08:23
immobilize and kill the food that they
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eat and so snake Venom's are destructive
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on a whole host of different levels so
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you are light you're justyou're you've
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got blood chemistry problems you've got
08:36
neurological issues happening you've got
08:38
cardiac issues happening a
08:40
depolarization of the muscle cells in
08:42
your heart you've got maybe all of these
08:44
things nephrotoxicity Myo toxicity
08:47
cytotoxicity cardio toxicity
08:49
neurotoxicity a snake bite can be a very
08:53
dangerous event in fact it can be a
08:55
lethal event and on a cellular level
08:57
it's catastrophic it's nothing to be
09:00
fooled with or taken lightly
09:02
there's no question about that okay it
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has been roughly 15 minutes that the
09:08
venom has been percolating inside of my
09:12
blood and I was the big moment well I'm
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curious about what I know you guys are
09:16
all curious about what exactly happened
09:18
to my blood with that venom inside so
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the first thing that we're gonna do is
09:22
put on my safety glasses always
09:25
important to have on safety glasses when
09:26
you're doing science experiments so
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we've got another blunt tip needle that
09:30
is the control that's the blood that's
09:32
in here and when I hold it up and look
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at it yeah that still looks super
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liquidy so what we're gonna do is pull
09:41
blood from each one of these vials and
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I'm gonna make a little streak just like
09:45
that on the top of this Plexiglas board
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we're gonna see what happens doesn't run
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down does it turn into jelly we don't
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know right yes interesting I guess we'll
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see and I'm just gonna try to make a
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nice little streak across here just like
10:01
that Wow
10:03
what that is some coagulation right
10:07
there isn't a car that's great
10:12
that looks like a zombie film right
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there so Carl tell us what happened
10:17
because there was no venom in there you
10:18
got these chunks of blood that just
10:20
looked like they vomited themselves down
10:22
this plexiglass plate when you expose
10:25
blood to oxygen you're gonna it's gonna
10:27
begin to clot right and so that's what
10:28
we're seeing there and that's that's
10:30
healthy blood then absolute healthy
10:32
blood exposed to oxygen is going to
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coagulate so for the most part looks
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like I'm healthy so now we are moving on
10:40
to the Copperhead that is our green vial
10:45
here and I'm just gonna give that a tilt
10:48
left and right now like you're saying
10:51
Carl that anticoagulant makes this look
10:55
like it's a whole lot very hard to say
10:57
if we're gonna see anything to the naked
10:59
eye but I assure you what's going on in
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that tube right now cellularly
11:03
is is as we talked about earlier
11:05
catastrophic okay so let's see if we can
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see anything with the naked eye here we
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go
11:09
Copperhead blood coming up wow look at
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all this bubbles I did not really see
11:18
that on the control okay here we go
11:21
oh wow look at that it's just dripping
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right out I'm not even applying any
11:25
pressure yet and look at that it's just
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dripping right out of the syringe
11:33
whoa look at that
11:35
boy it's certainly the naked eye it
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looks like it's less coagulation going
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on there right onto the naked I mean
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that just ran down where now he's I saw
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a couple a little micro maybe clots in
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there but but to the naked eye I don't
11:50
know about what you saw but yeah anyway
11:52
interesting that was blood running down
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that incredibly fast I mean just the
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pace at which it slid down and off the
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plexiglass you can see that a lot of the
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blood here still left streaking this was
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yes looked a lot you can almost see the
12:05
more watery consistency of it so that's
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that's the blood cells breaking down and
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not being able to hold on to each n to
12:11
the naked eye that's what it would look
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like again guys we can't stress enough
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how the internal aspects of what's
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happening on a micro level that if we
12:22
had a super powerful microscope we'd be
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able to see are happening I mean this is
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just explosions of blood cells and
12:28
everything breaking down apart and all
12:30
those little cell walls are being
12:31
affected and okay here we go
12:34
water moccasin you can see there the
12:38
blood definitely looks very thin as well
12:40
again a whole cocktail of proteins and
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toxins that are just turning this blood
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into who knows what
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again oh wow so that's that's having
12:54
trouble actually sucking the blood
12:57
robbing in the sample there we go okay
13:02
and my glasses are fogging off do my
13:05
best to keep my hand steady but even
13:07
interacting with venneman and blood yeah
13:10
it definitely gets your heart rate going
13:11
that's for sure that is my blood mixed
13:15
together with water moccasin venom and
13:18
again you can see that that blood just
13:20
wants to come out of the tip of the
13:22
needle without me applying any pressure
13:23
it's just dripping out on its own so I'm
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going to very slowly a little bit of
13:29
pressure there we go Wow look at that
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oh yeah look at that you just still see
13:41
all that it looks like a warm going down
13:43
the side of the Plexiglas but certainly
13:46
the Copperhead venom appeared thinner
13:48
and the cottonmouth venom in
13:50
relationship to the control tough to say
13:52
but maybe we're seeing some
13:54
anticoagulant activity there maybe so
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here we go I've got the Eastern
13:59
Diamondback venom in my blood they're
14:02
coming back
14:04
here we go
14:10
syringe going in again guys flat tip
14:13
needles even if I were to prick myself
14:15
with a needle with venom that is just
14:17
like suffering envenomations oh yeah
14:20
look at that look how thin that blood is
14:22
that pulls up way easier than the
14:25
Copperhead or the moccasin bowing out
14:27
look how watery that is that's crazy
14:30
what does human blood look like once
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it's been envenomated with Eastern
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diamondback rattlesnake venom here we go
14:38
one two three I think there isn't a
14:44
little bit regulation at Wow look at
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that that's some significant clotting
14:48
and remember on this one coyote Eastern
14:51
Diamondback venom we think they're both
14:53
anticoagulant and procoagulant activity
14:55
happening but that's interesting okay
14:59
well there we have it between the
15:01
control the Copperhead the moccasin and
15:03
the Eastern diamondback rattlesnake
15:04
visually across the board it looks like
15:06
there's quite a bit of difference right
15:08
even with the control I don't see any
15:09
speckling in the blood as compared to
15:11
these three but from your expert
15:13
perspective call what is it that we're
15:16
really seeing here I mean it looks like
15:17
a horror film but it's tough to tell
15:19
with the naked eye yeah so coyote you
15:22
know I think we need to point out that
15:24
this experiment is a really crude
15:27
experiment you know what we're seeing
15:29
we're kind of speculating a little bit
15:31
and based a little bit on what we know
15:33
about these given snake Venom's but this
15:35
really needs to be done under a
15:37
microscope in a really controlled
15:39
setting where we don't have this time
15:41
difference going on and we're not sure
15:43
you know that the amount of venom being
15:44
used is exact to get a real sense of
15:47
death but I think it's safe to say that
15:49
what's happening here whether or not we
15:51
can see it with the naked eye it's
15:54
serious and catastrophic damage on a
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cellular level and I think for everybody
15:58
out there watching not only did I hear
16:00
you say that we need to do this again
16:02
which means there will be a sequel to
16:03
this video but that the big takeaway is
16:06
the pit vipers in the United States have
16:09
the potential to be very dangerous this
16:10
is not a species you would ever want to
16:12
interact with in the wild and for
16:14
everybody out there that's asked coyote
16:15
will you get bitten by venomous snake
16:17
the answer is no you guys can see that
16:20
this is again catastrophic if you're
16:22
bitten by one of these snakes it is a
16:24
medical emergency with all of our
16:26
content we want to encourage the viewers
16:28
to admire these animals through safe
16:29
distance don't try to kill them don't
16:31
try to catch them
16:32
don't ever experiment with yourself to
16:34
see what would happen if you tangle no
16:36
flashes I think that's an excellent
16:38
synopsis and hey man are you gonna clean
16:41
this up I will yes I will clean up all
16:44
of the mess that I have made here in the
16:46
lab but for everybody out there watching
16:48
who's wanted to see what would happen if
16:49
coyote Peterson was bitten by a venomous
16:51
snake there you have it guys my blood
16:53
tangling with venom I'm coyote Peterson
16:56
be brave stay wild we'll see on the next
17:00
adventure
17:03
every year around the world people are
17:06
bitten by venomous snakes and it's
17:08
probably accurate to say that each and
17:10
every one of these bites happens by
17:12
accident some species like the
17:15
Copperhead aren't likely to kill you but
17:18
a full-on envenomations Eastern
17:20
diamondback is certain to take your life
17:23
without the administration of anti-venom
17:25
Karl and Marv performed thousands of
17:28
milkings every year risking their own
17:30
lives just in case you were
17:32
unfortunately bitten by one of these
17:34
slithering reptiles yet that doesn't
17:36
mean you should be afraid of snakes
17:38
almost all bites come as a result of
17:41
humans trying to move harass or kill one
17:44
of these animals the best course of
17:47
action is to always respect snakes from
17:49
a safe distance ensuring that you do not
17:52
have a catastrophic interaction if you
17:56
would like to learn more about snakes
17:57
and the power of their venom make sure
18:00
to visit the reptile Discovery Center's
18:02
website where you can schedule a snake
18:04
milking demonstration hey coyote pack if
18:08
you thought milking some of North
18:09
America's most deadly snakes was intense
18:11
make sure to go back and watch the
18:13
episode where we milked Australia's most
18:16
toxic snakes don't forget subscribe
18:19
click the notification valve and join
18:21
memberships so you can follow along with
18:23
me in the crew on our next wild
18:26
adventure